Bestselling Lab Cell Culture Microplates in 2020
Celltreat 229195 96 Clear Polystyrene Well Tissue Culture Plate with Lid, Sterile, 0.33 cm2 Cell Growth Area, Flat Bottom, Individual Pack (Pack of 50)
- Plates are labeled with alpha-numeric markings for easy identification of individual wells
- Each well has a raised rim which nests into the rings on the single direction lid to reduce evaporation and limit the risk of cross contamination
- Lids have a stacking ring for added stability when handling tall stacks of plates
- Manufactured from medical grade virgin polystyrene
- All multiple well plates are packaged sterile (gamma irradiated)
Microplate, Cell Culture (353654)
Edvotek 666 EDVA7 Plastic 96 Well Microtiter Plate Microplate, Transparent (Set of 6)
- Set of 6 plates
- 96 Well plastic microtiter plates
- The transparency facilitates easy viewing of color reactions
Microplate, Cell Culture (353225)
24-Well TC Treated Cell/Tissue Culture Plates, Individually Wrapped, Sterile, 100 Count
- Striation free, completely flat bases for even and consistent cell growth
- Optically clear with low autofluorescence for distortion free microscopy
- Low evaporation lid reduces evaporation and prevents contamination
- Exterior stacking ring on lid for added stability when stacking
- Well dimensions allow the use of specific tissue culture inserts
Microplate, Cell Culture (353961)
Microplate, Cell Culture (353963)
Microplate, Cell Culture (353230)
56 Eggs Hatching Incubator Automatic, Intelligent Digital Hatching with Turning Temp Control (US STOCK)
Greiner Bio-One 650101 Clear Polystyrene Microplate, Non-Sterile, Round (U) Bottom, 96 Well (Pack of 100)
- Free of detectable dnase, rnase, human dna
- Manufactured under din iso 9001 guidelines
- Suitable for +/- analyses
- Solid bottom
Microplate, Cell Culture (353962)
Corning 3595 Polystyrene Flat Bottom 96 Well TC-Treated Clear Microplate, With Low Evaporation Lid (Case of 50)
- Total well volume of 360L, with a recommended working volume of 75 to 200L; recommended medium insert volume of 0.32sq cm
- Clear polystyrene microplate has flat bottom wells; includes a nonreversable low evaporation lid with a condensation ring that helps to reduce contamination
- TC-treated for optimal cell attachment; sterilized by gamma radiation and certified nonpyrogenic
- Individual alphanumeric codes for well identification
Skin Cells Are Reprogrammed to Act like Embryonic Stem Cells
Find out how scientists turned regular skin cells into cells that act like embryonic stem cells, research that could eliminate the controversy surrounding the use of embryonic stem cells.
In a recent 2020 study, researchers have successfully been able to reprogram dermal (skin) fibroblast cells that are easily obtainable from any person, into an embryonic stem-like type cell. Embryonic stem cells are so beneficial because they are pluripotent, meaning they can differentiate into many kinds of cells. Embryonic stem cells have that potential built into them, because they are generating all the types of cells, tissues, and organ systems needed for a human being. The ability to create stem cells with the same potential from an accessible and almost limitless source, without having to use embryos, has amazing possibilities.
So how was it done? Skin cells were obtained and grown in culture in a laboratory. Now, pluripotent stem cells require certain signals to differentiate into certain cell types. In order to encourage the skin cells to change, or reprogram them to act like stem cells, the combination of 4 transcription factors, called KLF4, OCT4, SOX2 and C-MYC, were added to the growth media while the cells proliferated and grew. Transcription factors are proteins that can bind to DNA and control gene function by either regulating or suppressing the expression of certain genes, thus coaxing them to act like embryonic stem cells.
Once the cells were reprogrammed, the resulting cells had to be tested for function and morphology. Results indicated that the newly developed stem cells, which scientists called induced pluripotent stem (iPS) cells, were identical in biological structure, morphology, and function in comparison to their stem cell line, human embryonic stem cells (hESC). The iPS cells also had the same gene-expression profile as the hESC cells.
This is good news! If the newly developed iPS cells can act like stem cells, which tests indicate they do, they should have the potential to create important cells like beta islet cells to treat diabetes, or hematopoetic cells to create a blood supply for leukemia patients, or neuron cells for Parkinson's patients. In addition, if the skin cells can be harvested directly from the patient who, for example, needs muscle cells to repair muscle damage, then there would be no rejection issues. The possibilities are endless! These cells could potentially help with the treatment or even the cure of many diseases.
Lowry, WE et al. Generation of human induced pluripotent stem cells from dermal fibroblasts. PNAS February 26, 2020 vol. 105 no. 8 2883-288.